Asymmetric total synthesis of (+)-cardio
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S. Chandrasekhar; N. Kiranmai
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Article
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2010
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Elsevier Science
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French
β 288 KB
The stereoselective total synthesis of (+)-cardiobutanolide, a polyhydroxylated natural product, is achieved in high yield through Lu and Guo diene synthesis, Sharpless asymmetric dihydroxylation, and one-pot deprotection-lactonization. The utility of a recyclable reagent system in PEG for asymmetri