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Asymmetric Synthesis of (+)-Cardiobutanolide.

✍ Scribed by Ashish Garg; Ravi P. Singh; Vinod K. Singh


Book ID
102002008
Publisher
John Wiley and Sons
Year
2007
Weight
12 KB
Volume
38
Category
Article
ISSN
0931-7597

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Asymmetric total synthesis of (+)-cardio
✍ S. Chandrasekhar; N. Kiranmai πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 French βš– 288 KB

The stereoselective total synthesis of (+)-cardiobutanolide, a polyhydroxylated natural product, is achieved in high yield through Lu and Guo diene synthesis, Sharpless asymmetric dihydroxylation, and one-pot deprotection-lactonization. The utility of a recyclable reagent system in PEG for asymmetri