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Asymmetric synthesis of (+)- and (−)-7-(3-pyridyl)-1-azabicyclo[2.2.1]heptane as conformationally restricted analogues of nicotine

✍ Scribed by Thomas Ullrich; Dieter Binder; Michael Pyerin

Book ID: 104232030
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 61 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)01985-2

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✦ Synopsis

Both enantiomers of the conformationally restricted nicotine analogue 7-(3-pyridyl)-1-azabicyclo[2.2.1]heptane were prepared in a convenient, asymmetric synthetic route.

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