𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Asymmetric Synthesis of ACE Inhibitor-Benazepril HCl via a Bioreductive Reaction.

✍ Scribed by Ching-Yao Chang; Teng-Kuei Yang


Book ID
101954551
Publisher
John Wiley and Sons
Year
2003
Weight
148 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Asymmetric synthesis of ACE inhibitor-Be
✍ Ching-Yao Chang; Teng-Kuei Yang πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 207 KB

An enantioselective synthesis of the potent angiotensin converting enzyme (ACE) inhibitor (2S, 3%S)-2-(1-carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylamino)-4-phenylbutyric acid ethyl ester hydrochloride, Benazepril HCl 4, has been achieved through an asymmetric reduction of 4-(2-nit

Potent glycosidase inhibitors via hetero
✍ A. Defoin; Th. Sifferlen; J. Streith; I. DosbaΓ’; M.-J. Foglietti πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 186 KB

Some straightforward chemical transformations of oxazine diol 4, which was obtained from sorbaldehyde 2 by an asymmetric hetero Diels-Alder reaction followed by osmylation, led to the protected dihydroxypyrrolidine-aldehyde 8a and, after basic epimerisation, to 8b. Reduction of the aldehyde moiety a