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Asymmetric Synthesis of (−)-7-Epiaustraline and (+)-1,7-Diepiaustraline †

✍ Scribed by Tang, Minyan; Pyne, Stephen G.


Book ID
125888161
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
256 KB
Volume
68
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Synthesis of (1R,2R
✍ S. E. DENMARK; B. HERBERT 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Synthesis of (1R,2R,3R,7R,7aR)-Hexahydro-3-(hydroxymethyl)-1Hpyrrolizine-1,2,7-triol: 7-Epiaustraline. -Title compound (VI) is synthesized from known nitronate (I), prepared via [4 + 2] cycloaddition, in order to establish [4 + 2]/[3 + 2] cycloaddition chemistry as a general strategy for the synthe