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Asymmetric Synthesis of 2-Alkyl-Substituted 2-Hydroxyglutaric Acid γ-Lactones.

✍ Scribed by Anne Paju; Marit Laos; Artur Jogi; Malle Paeri; Raissa Jaeaelaid; Tonis Pehk; Tonis Kanger; Margus Lopp

Publisher
John Wiley and Sons
Year
2006
Weight
18 KB
Volume
37
Category
Article
ISSN
0931-7597

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1H and 13C NMR study of 2-hydroxyglutari
1H and 13C NMR study of 2-hydroxyglutaric acid and its lactone
✍ Dominika Bal; Adam Gryff-Keller 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB

## Abstract Determination of the level and absolute configuration of 2‐hydroxyglutaric acid in a patient's urine is a method of diagnosing two metabolic diseases. Such a determination can be done with the aid of NMR spectroscopic methods. In this paper the careful interpretation of ^1^H and ^13^C N