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Asymmetric Synthesis of 2-(2-Pyridyl)aziridines from 2-Pyridineimines Bearing Stereogenic N -Alkyl Substituents and Regioselective Opening of the Aziridine Ring

✍ Scribed by Savoia, Diego; Alvaro, Giuseppe; Di Fabio, Romano; Gualandi, Andrea; Fiorelli, Claudio


Book ID
120800737
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
283 KB
Volume
71
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Regioselective Nucl
✍ B. G. M. BURGAUD; D. C. HORWELL; A. PADOVA; M. C. PRITCHARD πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 36 KB πŸ‘ 1 views

Regioselective Nucleophilic Ring Opening Reactions of 2,2-Disubstituted Aziridines -The Asymmetric Synthesis of Ξ±,Ξ±-Disubstituted Amino Acids. -It is shown that, under appropriate conditions, 2,2disubstituted aziridines like (I) and (V) undergo regioselective ring opening reactions at C-3 with carb