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Asymmetric synthesis and structure activity relationship of the four stereoisomers of the antibiotic amidinomycin

✍ Scribed by S.Y. Sung; M. Kist; A.W. Frahm


Book ID
117628734
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
103 KB
Volume
4
Category
Article
ISSN
0928-0987

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Asymmetric Synthesis and Structure-Activ
✍ Sun-Young Sung; Manfred Kist; August W. Frahm πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 291 KB

The stereoisomers of amidinomycin 7 and their intermediates 1-6, which are produced from homochiral 3-oxocyclopentanecarboxylic acids by asymmetric synthesis, are tested for their antimicrobial effects by agar diffusion test and by Bouillon serial dilution assay. Their antibiotic activities against