Asymmetric Michael addition of α-fluoro-α-phenylsulfonyl ketones to nitroolefins catalyzed by phenylalanine-based bifunctional thioureas
✍ Scribed by Hai-Feng Cui; Peng Li; Xiao-Wei Wang; Shi-Zheng Zhu; Gang Zhao
- Book ID
- 113711505
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 493 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0022-1139
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📜 SIMILAR VOLUMES
## Abstract A highly enantioselective Michael reaction of aromatic ketones with nitroolefins was accomplished in the presence of a chiral bifunctional primary amine–thiourea catalyst and 4‐nitrobenzoic acid as the co‐catalyst; the corresponding adducts were obtained in excellent enantioselectivitie
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