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Asymmetric Michael addition of thiols to (1R,2R,4R)-(−)-2,10-N-enoylcamphorsultam

✍ Scribed by Wen-Jiuan Tsai; Yi-Tsong Lin; Biing-Jiun Uang


Book ID
103977049
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
237 KB
Volume
5
Category
Article
ISSN
0957-4166

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2R,3R)-Dihydroxy-tetrahydronaphthalene, prepared via an efficient chemoenzymatic procedure from naphthalene, has been successfully tested, as a chiral auxiliary in diastereoselective conjugate additions of lithium dialkylcuprates to 0t,13-unsaturated esters and in stereoselective alkylations of 13-k