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Highly stereoselective addition of 2-trimethylsilyloxyfuran to N-glyoxyloyl-(2R)-bornane-10,2-sultam

โœ Scribed by Tomasz Bauer


Book ID
103977453
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
166 KB
Volume
7
Category
Article
ISSN
0957-4166

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The asymmetric ene reaction of N-glyoxyloyl-(2R)-bomane-10,2-sultam 2 and its hemiacetal 3 with 1-pentene 4 and 1-hexene 5 in the presence of Lewis acids is reported. All the ene reactions studied led to diastereoisomeric mixtures of olefins 6 and 7 or 8 and 9, with predominance of products of the (