Asymmetric imine isomerisation in the enantioselective synthesis of chiral amines from prochiral ketones
β Scribed by Johannes G.H Willems; Johannes G de Vries; Roeland J.M Nolte; Binne Zwanenburg
- Book ID
- 103408656
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 225 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract Asymmetric catalytic activity of the chiral spiroborate esters **1**β**9** with a O~3~BN framework (see __Fig.β 1__) toward borane reduction of prochiral ketones was examined. In the presence of 0.1β equiv. of a chiral spiroborate ester, prochiral ketones were reduced by 0.6β equiv. of bor
## Abstract Novel chiral Schiff bases were synthesized from (+)βcamphor, and their application to asymmetric transfer hydrogenation of prochiral ketones is described. The asymmetric transfer hydrogenation reaction could afford excellent conversion rates (up to 97.3%) and up to 27.3% enantiomeric ex