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Synthesis of novel chiral Schiff bases and their application in asymmetric transfer hydrogenation of prochiral ketones

✍ Scribed by Zhongqiang Zhou; Yongjun Bian


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
100 KB
Volume
19
Category
Article
ISSN
1042-7163

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✦ Synopsis


Abstract

Novel chiral Schiff bases were synthesized from (+)‐camphor, and their application to asymmetric transfer hydrogenation of prochiral ketones is described. The asymmetric transfer hydrogenation reaction could afford excellent conversion rates (up to 97.3%) and up to 27.3% enantiomeric excess. Β© 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:682–687, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20494


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