Asymmetric hydrogenation catalyzed by a chiral ferrocenylphosphine-rhodium complex
โ Scribed by Tamio Hayashi; Takaya Mise; Seiko Mitachi; Keiji Yamamoto; Makoto Kumada
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 120 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
A palladium complex bearing chiml (hydroxyalkyl)ferrocenylphosphine ligand was found to be a highly regio-and stereoselective catalyst for the asymmetric allylic amination of 2butenyl acetates with benzylamine, the nucleophilic attack of the amine taking place selectively on the more substituted end
Effective catalytic asymmetric hydrogenations catalyzed by chiral pyrrolidinephosphine-rhodium complexes have been proven to be useful for the preparation of optically active a-amino acids @3-91%)2'3), isoquinoline salsolidine (45%)6) cc-hydroxy esters (78.5%)4'5), R-(-)-pantolactone C80.5-86.7%17'g
## Abstract A novel chelated ferroceneโbased planar chiral Nโheterocyclic carbeneโRh(I) complex was synthesized by a simple method. It was applied to the asymmetric transfer hydrogenation of prochiral ketones. Enantioselectivities of up to 67% ee were observed. Copyright ยฉ 2009 John Wiley & Sons, L