Asymmetric Diels-Alder Reactions of Chiral Acrylates of Cholic Acid Derivatives
✍ Scribed by Mathivanan, Packiarajan; Maitra, Uday
- Book ID
- 121331644
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 860 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
In the presence of a cinchona alkaloid as a catalyst, the Diels-Alder reaction of 3-hydroxy-2-pyrone with chiral N-acryloyl oxazolidinone afforded a bicyclolactone adduct with high diastereoselectivities (up to 95%de) in almost quantitative yield.
## Abstract Starting from the enantiomerically pure monoterpenes (+)‐pulegone (**3**), (+)‐limonene (**7**), (−)‐β‐pinene (**9**), (+)‐ and (−)‐camphor (**13**) or (+)‐cholestenone (**11**) the chiral alcohols **4, 5, 6, 8, 10, 12, 14, 15, 16, 17** et **18** were prepared; their acrylates **II** un