Asymmetric catalytic hydrogenation of α-amino ketones by cationic iridium complexes
✍ Scribed by E. Cesarotti; L. Prati; M. Pallavicini; L. Villa; R. Spogliarich; E. Farnetti; M. Graziani
- Publisher
- Elsevier Science
- Year
- 1990
- Weight
- 262 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0304-5102
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Cationic [Ir(COD)(LL)]+ species (LL = cr-diimines derived from biacetyl or glyoxal) in the presence of KOH are active catalysts in the homogeneous hydrogen transfer from isopropanol to acetophenone to give phenylethanol. The most active species is the cation containing biacetyloximehydrazone.
Chiral ruthenium hydrides : HRuCl(TRPC)2 and H2Ru(TBPC)2 catalyse the hydrogenation of a-&unsaturated ketones to ketones (e.e. 62 X). Asymmetric hydrogenation of prochiral olefins in the presence of chiral rhodium catalyst 1 is now a useful preparative tool for many a-aminoacids