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Asymmetric catalysis of the Strecker amino acid synthesis by a cyclic dipeptide

✍ Scribed by M. S. Iyer; K. M. Gigstad; N. D. Namdev; M. Lipton


Publisher
Springer
Year
1996
Tongue
English
Weight
634 KB
Volume
11
Category
Article
ISSN
0939-4451

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Efficient asymmetric synthesis of Ξ±-amin
✍ Tatsuhiko Kanmera; Sannamu Lee; Haruhiko Aoyagi; Nobuo Izumiya πŸ“‚ Article πŸ“… 1979 πŸ› Elsevier Science 🌐 French βš– 290 KB

A series of cycZo(Aaminoacyl-L-Ala) (fl) (A=a,@dehydro) were prepared from cycZo(Gly-L-Ala) and corresponding aldehyde, and hydrogenated with Pd black in MeOH. Chiral inductions producing CycZo(L-aminoacyl-L-Ala) (2) from 2 were 96-99% in the case of L-Aba (2-eminobutanoic acid), L-Val, L-Leu, and L