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Asymmetric synthesis of a novel phenylogous amino acid mimicking an extended dipeptide

✍ Scribed by Li Chen; Richard V. Trilles; Jefferson W. Tilley


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
396 KB
Volume
36
Category
Article
ISSN
0040-4039

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Azabicyclo[X.Y.0] alkane amino acids are rigid dipeptide b-turn mimetics with great potential applications for drug discovery. The lack of efficient methods to synthesize these compounds is a major bottleneck in this field. Herein we report an efficient approach to the enantiopure synthesis of (3S,6