Conjugate Addition Reactions of Configurationally Stable Benzylic and Allylic Organolithium Species. -The organolithium species generated from the amines (I) and (IV), BuLi, and (-)-sparteine react with double activated olefins and nitro olefins to provide addition products in good yields with high
✦ LIBER ✦
Asymmetric Carbon−Carbon Bond Formation in Michael Reactions: Conjugate Addition Reactions of Configurationally Stable Benzylic and Allylic Organolithium Species
✍ Scribed by Curtis, M. D.; Beak, P.
- Book ID
- 118218089
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 180 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3263
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The choice of the ligand can provide control of 1,2-vs. 1,4-addition of organolithium species to α,β-unsaturated carbonyl substrates. With (-)-sparteine as ligand highly enantioenriched configurationally stable α-lithio benzylic and allylic amine derivatives in asymmetric Michael additions give prod
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## Abstract For Abstract see ChemInform Abstract in Full Text.
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