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Asymmetric Carbon−Carbon Bond Formation in Michael Reactions: Conjugate Addition Reactions of Configurationally Stable Benzylic and Allylic Organolithium Species

✍ Scribed by Curtis, M. D.; Beak, P.


Book ID
118218089
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
180 KB
Volume
64
Category
Article
ISSN
0022-3263

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📜 SIMILAR VOLUMES


ChemInform Abstract: Asymmetric Carbon—C
✍ M. D. Curtis; P. Beak 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Conjugate Addition Reactions of Configurationally Stable Benzylic and Allylic Organolithium Species. -The organolithium species generated from the amines (I) and (IV), BuLi, and (-)-sparteine react with double activated olefins and nitro olefins to provide addition products in good yields with high

ChemInform Abstract: Ligand Control and
✍ Y. S. PARK; G. A. WEISENBURGER; P. BEAK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 41 KB 👁 2 views

The choice of the ligand can provide control of 1,2-vs. 1,4-addition of organolithium species to α,β-unsaturated carbonyl substrates. With (-)-sparteine as ligand highly enantioenriched configurationally stable α-lithio benzylic and allylic amine derivatives in asymmetric Michael additions give prod