The asymmetric addition of trimethylsily
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Yuri N Belokon; Brendan Green; Nicolai S Ikonnikov; Michael North; Vitali I Tara
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Article
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1999
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Elsevier Science
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French
⚖ 217 KB
The use of a bimetallic titanium salen complex as a catalyst for the asymmetric addition of trimethylsilylcyanide to ketones is reported. The cyanohydrin trimethyisilyl ethers are obtained with enantiomeric excesses of up to 72% from reactions carried out at room temperature and atmospheric pressure