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Asymmetric addition of trimethylsilyl cyanide to aldehydes catalysed by chiral (salen)TiIV complexes

✍ Scribed by Belokon', Yuri; Flego, Massimilano; Ikonnikov, Nicolai; Moscalenko, Margarita; North, Michael; Orizu, Charles; Tararov, Vitali; Tasinazzo, Michela


Book ID
121672367
Publisher
Royal Society of Chemistry
Year
1997
Weight
200 KB
Volume
9
Category
Article
ISSN
1472-7781

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The asymmetric addition of trimethylsily
✍ Yuri N Belokon; Brendan Green; Nicolai S Ikonnikov; Michael North; Vitali I Tara πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 217 KB

The use of a bimetallic titanium salen complex as a catalyst for the asymmetric addition of trimethylsilylcyanide to ketones is reported. The cyanohydrin trimethyisilyl ethers are obtained with enantiomeric excesses of up to 72% from reactions carried out at room temperature and atmospheric pressure