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Associations between genetic polymorphisms of Phase I and II metabolizing enzymes, p53 and susceptibility to esophageal adenocarcinoma

โœ Scribed by A.G Casson; Z Zheng; D Chiasson; K MacDonald; D.C Riddell; J.R Guernsey; D.L Guernsey; J McLaughlin


Book ID
114238156
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
90 KB
Volume
27
Category
Article
ISSN
0361-090X

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We examined the effect of genetic polymorphisms of phase-II enzymes, glutathione S-transferase P1 (GSTP1) and N-acetyltrans-ferase2 (NAT2) on susceptibility to esophageal squamous-cell carcinoma. To determine the genotypes of the 2 polymorphisms, PCR-based analysis was performed on samples from 66 J