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Association study of the p53-gene Pro72Arg polymorphism in schizophrenia

โœ Scribed by Hsien-Jane Chiu; Ying-Chieh Wang; Jen-Yeu Chen; Chen-Jee Hong; Shih-Jen Tsai

Book ID
117333938
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
81 KB
Volume
105
Category
Article
ISSN
0165-1781

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## Abstract It is well known that the TP53 gene considerably influences on DNA repair processes. Polymorphisms in the TP53 gene, particularly the wellโ€known Arg72Pro in codon 72 of exon 4 (Ex4+119 G>C; rs1042522), can modify the functionality of the p53 protein and activation of DNA repair. Actuall