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Association study of brain-derived neurotrophic factor in adults with a history of childhood onset mood disorder

✍ Scribed by Strauss, J. ;Barr, C.L. ;George, C.J. ;King, N. ;Shaikh, S. ;Devlin, B. ;Kovacs, M. ;Kennedy, J.L.


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
66 KB
Volume
131B
Category
Article
ISSN
0148-7299

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/βˆ’^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, dose‐