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Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder

โœ Scribed by Matthew Lanktree; Alessio Squassina; Marilee Krinsky; John Strauss; Umesh Jain; Fabio Macciardi; James L. Kennedy; Pierandrea Muglia


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
107 KB
Volume
147B
Category
Article
ISSN
1552-4841

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/โˆ’^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, doseโ€