Association ofp53codon 72 genetic polymorphism with the risk of ulcerative colitis in northern Iran
β Scribed by Salaheddin Vaji; Zivar Salehi; Keyvan Aminian
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 131 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0179-1958
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Background: Human papillomavirus (hpv) plays an important role in the development of carcinomas at various body sites. it was found previously that the p53 codon 72 polymorphism (c/g) is a high-risk factor for the development hpv-associated cervical carcinoma. however, it still was considered co
A single nucleotide polymorphism (SNP) in the promoter of MDM2 gene, SNP309 T>G (a T-G exchange at nucleotide 309 in the first intron), can increase the expression level of MDM2, thereby causing an impairment of p53 tumor suppressor activity. A G-C exchange at p53 codon 72 polymorphism results in a