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Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population

✍ Scribed by Martínez, Alfonso; del Carmen Martín, Maria; Mendoza, Juan L; Taxonera, Carlos; Díaz-Rubio, Manuel; de la Concha, Emilio G; Urcelay, Elena

Book ID
110026533
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
92 KB
Volume
14
Category
Article
ISSN
1018-4813

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The organic cation transporter OCTN1 (SLC22A4) is expressed ubiquitously, with strong expression in kidney, trachea, bone marrow, and fetal liver, and it mediates transport of organic cations in a pH-dependent manner. Recent studies have identified single nucleotide polymorphisms (SNPs) of OCTN1 in