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Functional variants of OCTN cation transporter genes are associated with Crohn disease

✍ Scribed by Peltekova, Vanya D; Wintle, Richard F; Rubin, Laurence A; Amos, Christopher I; Huang, Qiqing; Gu, Xiangjun; Newman, Bill; Oene, Mark Van; Cescon, David; Greenberg, Gordon


Book ID
109918989
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
662 KB
Volume
36
Category
Article
ISSN
1061-4036

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Filaggrin loss-of-function variants are
✍ J. Van Limbergen; R.K. Russell; E.R. Nimmo; Y. Zhao; H. Liao; H.E. Drummond; G. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 100 KB

Background: Pediatric inflammatory bowel disease (IBD) has a high prevalence of coexistent atopy. Filaggrin (FLG) loss-of-function variants (null-alleles) are associated with eczema and asthma in association with eczema. The aim was to assess the contribution of FLG null-alleles to pediatric IBD sus