E701p antibodies was associated with a shorter disease free interval ( P = 0.012) and poor survival (P = 0.049). However, this variable possessed no prognostic value after adjusting for FIGO stage and tumor size. Conclusions. The authors' findings indicate that the prognostic significance of serum
Association of the antibodies against human papillomavirus 16 E4 and E7 proteins with cervical cancer positive for human papillomavirus DNA
β Scribed by Takashi Onda; Tadahito Kanda; Soichi Zanma; Toshiharu Yasugi; Sumie Watanabe; Takashi Kawana; Kuniaki Ueda; Hiroyuki Yoshikawai; Yuji Taketani; Kunito Yoshiike
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 698 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0020-7136
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## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh
Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel
Sera from I 18 women of 33 to over 90 years of age, with or without a history of cervical squamous-cell carcinoma, were examined for the presence of antibodies to HPV-6b, HPV-I6 and HPV-18 LI, U, E4, and E7 gene products by the use of bacterially derived P-Gal fusion proteins and Western-blot analys