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Association of interleukin-4 and interleukin-1B gene variants with Larsen score progression in rheumatoid arthritis

✍ Scribed by Genevay, St�phane ;Di Giovine, Francesco S. ;Perneger, Thomas V. ;Silvestri, Tania ;Stingelin, Sibylle ;Duff, Gordon ;Guerne, Pierre-Andr�


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
104 KB
Volume
47
Category
Article
ISSN
0004-3591

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## Objective Recent evidence has highlighted a major genetic contribution to radiographic damage in rheumatoid arthritis (RA). The objective of this study was to determine whether genetic variants in the loci for interleukin-1 (IL-1), IL-6, IL-10, protein tyrosine phosphatase N22 (PTPN22), and sele