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Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer

✍ Scribed by Ito, I; Yoshimoto, M; Iwase, T; Watanabe, S; Katagiri, T; Harada, Y; Kasumi, F; Yasuda, S; Mitomi, T; Emi, M


Book ID
109837212
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
744 KB
Volume
71
Category
Article
ISSN
0007-0920

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Primary breast tumors were tested for loss of heterozygosity (LOH), on chromosome 9p with microsatellite markers restricted to a 28 cM region including the MTSl gene. LOH was found with at least I marker in 38% of the 20 I cases analyzed. A high frequency of deletions was detected at the 9p23-pZI re