𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Association of dopamine D2 receptor molecular variant with schizophrenia

✍ Scribed by T. Arinami; H. Hamaguchi; M. Itokawa; H. Enguchi; H. Tagaya; S. Yano; M. Toru; H. Shimizu


Book ID
118555512
Publisher
The Lancet
Year
1994
Tongue
English
Weight
315 KB
Volume
343
Category
Article
ISSN
0140-6736

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


No association of dopamine D2 receptor m
✍ Chen, Chia-Hsiang; Chien, Shih-Hsiang; Hwu, Hai-Gwo πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 305 KB πŸ‘ 1 views

A serine-to-cysteine mutation of dopamine D2 receptor at codon 311 (Cys311) was found to have higher frequency in schizophrenic patients than in normal controls in Japanese by Arinami et al. 11994: Lancet 343: 703-7041. The Cys311 allele was found to be associated with patients with younger ageof-on

Lack of association between dopamine D2
✍ Tanaka, Toshihisa; Igarashi, Shuichi; Onodera, Osamu; Tanaka, Hajime; Fukushima, πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 12 KB πŸ‘ 2 views

reported identifying one missense nucleotide mutation from C to G resulting in a substitution of serine with cysteine at codon 311 in the third intracellular loop of the dopamine D2 receptor in schizophrenics. Arinami et al. 119941 reported finding a positive association between the Cys311 variant a

Further association study on dopamine D2
✍ Arinami, Tadao; Itokawa, Masanari; Aoki, Junichi; Shibuya, Haruo; Ookubo, Yoshir πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 40 KB πŸ‘ 1 views

The dopamine D2 receptor gene is a candidate gene for schizophrenia because the potency of certain neuroleptics correlates with their affinity for this receptor, Casecontrol studies in 291 schizophrenics, 78 patients with affective disorders, and 579 controls on an association of a molecular variant