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Association of a variation in the promoter region of the brain-derived neurotrophic factor gene with familial Parkinson's disease

✍ Scribed by Abbas Parsian; Rashmi Sinha; Brad Racette; Jing H Zhao; Joel S Perlmutter

Book ID: 116819939
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 119 KB
Volume: 10
Category: Article
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2003.12.003

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## Abstract Potential roles for variants in the human __BDNF__ gene in human brain disorders are supported by findings that include: (a) influences that this trophic factor can exert on important neurons, brain regions, and neurotransmitter systems, (b) changes in __BDNF__ expression that follow al