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Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease

✍ Scribed by Sara M. Bodner; Wade Berrettini; Vivianna van Deerlin; David A. Bennett; Robert S. Wilson; John Q. Trojanowski; Steven E. Arnold


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
72 KB
Volume
134B
Category
Article
ISSN
1552-4841

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## Abstract Huntington's disease (HD) is a neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms and by a progressive degeneration of neurons in basal ganglia and in brain cortex. Brain‐derived neurotrophic factor (BDNF) is a pro‐survival factor for striatal neurons