Mutation screen of the brain derived neu
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S. Friedel; F. Fontenla Horro; A.K. Wermter; F. Geller; A. Dempfle; K. Reichwald
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Article
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2005
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John Wiley and Sons
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English
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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/โ^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, doseโ