A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer’s disease
✍ Scribed by Kunugi, H; Ueki, A; Otsuka, M; Isse, K; Hirasawa, H; Kato, N; Nabika, T; Kobayashi, S; Nanko, S
- Book ID
- 110059250
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 120 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1359-4184
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract We studied two genetic polymorphisms (240C/T and 480G/A) of the brain‐derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The di
## Abstract Potential roles for variants in the human __BDNF__ gene in human brain disorders are supported by findings that include: (a) influences that this trophic factor can exert on important neurons, brain regions, and neurotransmitter systems, (b) changes in __BDNF__ expression that follow al