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A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer’s disease in patients lacking the Apolipoprotein E ε4 allele

✍ Scribed by Riemenschneider, M; Schwarz, S; Wagenpfeil, S; Diehl, J; Müller, U; Förstl, H; Kurz, A


Book ID
110059426
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
86 KB
Volume
7
Category
Article
ISSN
1359-4184

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The apolipoprotein E ε2 allele is associ
✍ Cornelia M. van Duijn; Peter de Knijff; Anita Wehnert; Joke De Voecht; Juliana B 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 652 KB

It was suggested that in contrast to the E4 allele, the E2 allele of the apolipoprotein E gene (APOE"2) has a protective effect for late-onset Alzheimer's disease and early-onset Alzheimer's disease (EOAD). We studied the role of the APOE\*2 allele in the pathogenesis of EOAD in a Dutch population-b