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Association of a polymorphism in the ABCB1 gene with Parkinson's disease

✍ Scribed by Marie Westerlund; Andrea Carmine Belin; Anna Anvret; Anna Håkansson; Hans Nissbrandt; Charlotta Lind; Olof Sydow; Lars Olson; Dagmar Galter

Book ID
116820605
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
105 KB
Volume
15
Category
Article
ISSN
1353-8020

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✍ Dr. David G. le Couteur; Peter W. Leighton; Sally J. McCann; Susan M. Pond 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB 👁 1 views

## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.