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Association of paraoxonase 1 gene polymorphisms with risk of Parkinson’s disease: a meta-analysis

✍ Scribed by Elias Zintzaras; Georgios M. Hadjigeorgiou


Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
267 KB
Volume
49
Category
Article
ISSN
1435-232X

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.