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Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease

✍ Scribed by Andrea Carmine Belin; Caroline Ran; Anna Anvret; Silvia Paddock; Marie Westerlund; Anna Håkansson; Hans Nissbrandt; Peter Söderkvist; Nil Dizdar; Ahmad Ahmadi; Maria Anvret; Thomas Willows; Olof Sydow; Dagmar Galter

Book ID
116774234
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
219 KB
Volume
522
Category
Article
ISSN
0304-3940

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Further evidence for an association of the Paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease
✍ Andrea Carmine; Silvia Buervenich; Olof Sydow; Maria Anvret; Lars Olson 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 54 KB 👁 1 views

Paraoxonase1 (PON1) is an arylesterase mainly expressed in the liver that hydrolyzes organophosphates such as pesticides, reported risk factors for Parkinson's disease (PD), and other neurotoxins. A Leu-Met 54 polymorphism in the gene for PON1-affecting enzyme activity was recently shown, employing