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Association between the SORL1 rs2070045 polymorphism and late-onset Alzheimer's disease: Interaction with the ApoE genotype in the Chinese Han population

โœ Scribed by Xue, Xiaofan; Zhang, Milan; Lin, Yicong; Xu, Erhe; Jia, Jianping

Book ID
122132639
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
903 KB
Volume
559
Category
Article
ISSN
0304-3940

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Although the pathogenetic mechanisms driving Alzheimer's disease (AD) are unclear, genetic variations may play an important role. Previous studies have identified that single nucleotide polymorphisms (SNPs) in the sortilin-related receptor, L (DLR class) A repeats containing (SORL1) gene are associa