Although the pathogenetic mechanisms driving Alzheimer's disease (AD) are unclear, genetic variations may play an important role. Previous studies have identified that single nucleotide polymorphisms (SNPs) in the sortilin-related receptor, L (DLR class) A repeats containing (SORL1) gene are associa
โฆ LIBER โฆ
The SORL1 polymorphism rs985421 may confer the risk for amnestic mild cognitive impairment and Alzheimer's disease in the Han Chinese population
โ Scribed by Jin, Chunhui; Zhang, Lili; Xian, Yiping; Liu, Xiaowei; Wu, Yue; Zhang, Feng; Zhu, Jianzhong; Zhang, Guofu; Chen, Caixia; Gong, Ronglan; Zhang, Lingyun; Yuan, Jianmin; Zhang, Fuquan; Tian, Lin; Wang, Guoqiang; Cheng, Zaohuo
- Book ID
- 121801783
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 672 KB
- Volume
- 563
- Category
- Article
- ISSN
- 0304-3940
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## Abstract ## Objectives To design and validate a new screening test for amnestic Mild Cognitive Impairment (AโMCI) and early stage Alzheimer's disease (AD). ## Methods We develop a verbal episodic and semantic memory test: the Memory Alteration Test (M@T). Discriminative validity was assessed
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