Association between the 102T/C polymorphism of serotonin-2A receptor gene and schizophrenia among south Indians
β Scribed by Araga, U S; Narasu, M L
- Book ID
- 110059403
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 56 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1359-4184
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Several pieces of evidence implicate serotonin receptors in the aetiology of schizophrenia, and recently a number of studies have reported a genetic association between the 102T/C polymorphism of serotonin receptor type 2A gene and schizophrenia. Unfortunately a number of failures to replicate these
Sixty-two patients with schizophrenia and 96 normal controls were investigated for genetic association with restriction fragment length polymorphisms (RFLPs) in the serotonin receptor genes. A positive association between the serotonin 2A receptor gene (HTR2A) and schizophrenia was found, but not be