Association between the serotonin 2A receptor gene and tardive dyskinesia in chronic schizophrenia
β Scribed by Segman, R H; Heresco-Levy, U; Finkel, B; Goltser, T; Shalem, R; Schlafman, M; Dorevitch, A; Yakir, A; Greenberg, D; Lerner, A
- Book ID
- 110059297
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 125 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1359-4184
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Sixty-two patients with schizophrenia and 96 normal controls were investigated for genetic association with restriction fragment length polymorphisms (RFLPs) in the serotonin receptor genes. A positive association between the serotonin 2A receptor gene (HTR2A) and schizophrenia was found, but not be
## Abstract Tardive dyskinesia (TD) occurs in approximately 20% of patients exposed to longβterm antipsychotic treatment and may be influenced by genetic predisposition, in addition to clinical risk factors. In this study, we implemented a twoβstep approach to identify susceptibility genes for TD.