Association between serotonin transporter gene and borderline personality disorder
β Scribed by Xingqun Ni; Kirsten Chan; Natalie Bulgin; Tricia Sicard; Ramprasad Bismil; Shelley McMain; James L. Kennedy
- Book ID
- 113750142
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 118 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-3956
No coin nor oath required. For personal study only.
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Human family and twin studies have established considerable heritable components in personality traits as assessed by selfreport questionnaires. Recently, an association between a functional polymorphism in the upstream regulatory region of the serotonin transporter gene and neuroticismrelated perso
## Abstract ## **Objective:** The serotonin system has been implicated in mood and appetite regulation, and the serotonin transporter gene (__SLC6A4__) is a commonly studied candidate gene for eating pathology. However, most studies have focused on a single polymorphism (__5βHTTLPR__) in __SLC6A4_
## The frequent occurrence of depressive symptoms in patients with borderline personality disorder has generated considerable interest in the nature of the relationship between borderline personality disorder and the depressive disorders. Data from the perspectives of phenomenology, biology, family