Association between fragile X premutation and premature ovarian failure: a case–control study and meta-analysis
✍ Scribed by D. Tosh; K. L. Rao; H. S. Rani; D. A. Deenadayal; U. S. N. Murty; P. Grover
- Book ID
- 121843230
- Publisher
- Springer
- Year
- 2014
- Tongue
- English
- Weight
- 571 KB
- Volume
- 289
- Category
- Article
- ISSN
- 0003-9128
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Early menopause in the fragile X carriers has been well documented in several reports. All surveys demonstrated that 13-25% of fragile X carriers experienced premature ovarian failure (POF), defined as menopause before the age of 40 years. In 1995 we started screening two groups of subjects as a par
The preliminary results of an international collaborative study examining premature menopause in fragile X carriers are presented. A total of 760 women from fragile X families was surveyed about their fragile X carrier status and their menstrual and reproductive histories. Among the subjects, 395 ca