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Association between dopamine transporter gene polymorphism and susceptibility to Parkinson's disease in Japan

✍ Scribed by Masataka Nishimura; Ryuji Kaji; Mitsuhiro Ohta; Ikuko Mizuta; Sadako Kuno

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 305 KB
Volume: 17
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.10187

No coin nor oath required. For personal study only.

✦ Synopsis

We studied a polymorphism in the dopamine transporter (DAT) gene in 236 Japanese patients with Parkinson's disease (PD) and compared the results with 220 controls. The 1215A/G genotype of the DAT gene was significantly different between PD patients and controls, suggesting a possible involvement of DAT in genetic susceptibility to PD.

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