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Association between chloroquine resistance phenotypes and point mutations in pfcrt and pfmdr1 in Plasmodium falciparum isolates from Thailand

✍ Scribed by Kanchana Rungsihirunrat; Wanna Chaijareonkul; Aree Seugorn; Kesara Na-Bangchang; Sodsri Thaithong


Book ID
116182185
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
281 KB
Volume
109
Category
Article
ISSN
0001-706X

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Prevalence of pfcrt point mutations and
✍ Carlo Severini; Michela Menegon; Anna Rosa Sannella; Maria Grazia Paglia; Pasqua πŸ“‚ Article πŸ“… 2006 πŸ› Elsevier Science 🌐 English βš– 133 KB

The development in Plasmodium falciparum of the resistance to chloroquine (CQ) constitutes a public health priority, due to its direct influence in childhood mortality. The molecular basis for CQ resistance (CQR) is still unclear but, recently, a new relevant gene, named pfcrt, with several point mu