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Assignment of the interleukin-2 receptor β chain gene (II-2rb) to band E on mouse chromosome 15

✍ Scribed by Campbell, Hugh D.; Webb, Graham C.; Kono, Takeshi; Taniguchi, Tadatsugu; Ford, Judith H.; Young, Ian G.


Book ID
123151330
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
193 KB
Volume
12
Category
Article
ISSN
0888-7543

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The IL-2 receptor β chain gene (Il-2rb)
✍ Thomas R. Malek; Vladimir Vincek; Biljana Gatalica; Maja Bucan 📂 Article 📅 1993 🏛 Springer-Verlag 🌐 English ⚖ 246 KB

A functional high-affinity IL-2 receptor (IL-2R) is comprised of at least three subunits (cz, [3, and 7) that cooperatively act to bind IL-2, leading to the growth of antigen-activated T lymphocytes (Hatakeyama et al. 1989;Takeshita et al. 1992). Mouse and human IL-2Rc~ chain genes (I1-2ra) have bee