𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Assignment of relative configurations and conformational study of acyclic diastereomeric ketones

✍ Scribed by C. Alvarez-Ibarra; M. S. Arias-Pérez; E. Moya

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
637 KB
Volume
28
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The conformational analysis and the assignment of relative configurations [(RR, SS) and (RS, SR)] to the dia‐stereomeric racemates of two acyclic ketones with two asymmetric carbons, ±‐2,2,7,7‐tetramethyl‐5,6‐diphenyloctan‐3‐one and ±‐5,5‐dimethyl‐1,3,4‐triphenylhexan‐1‐one, have been achieved by analysis of^1^H‐^1^H geminal and vicinal coupling constants, ^13^C–^1^H direct coupling constants and ^13^C chemical shifts. This study allows the establishment of the monoconformational character of the (RR, SS) diastereomers. The application of the empirical equation of Haasnoot et al. supports this hypothesis.

📜 SIMILAR VOLUMES

Standard values of vicinal coupling cons
Standard values of vicinal coupling constants in the assignment of relative configurations and conformational analysis of acyclic chiral carbinols and hydrocarbons
✍ C. Alvarez Ibarra; M. T. Garcia Romo; M. S. Arias Perez 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 424 KB 👁 1 views

## Abstract Standard values of vicinal coupling constants are proposed in order to assign relative configuratations and analyse the conformational distribution of acyclic chiral carbinols and hydrocarbons. Thus, the assignment of relative configurations has been achieved for the diastereomeric carb

Assignment of relative configurations to
Assignment of relative configurations to acyclic diastereomeric carbinols with the lanthanide shift reagent Eu (fod)3 by 1H and 13C NMR
✍ C. Alvarez Ibarra; M. L. Quiroga Feijoo; M. S. Arias Perez; J. de la Orden Parra 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB

An assignment of relative configurations has been achieved for the diastereomeric racernates(lR2R,lS2S) and (1R2S, 1S2R) of 3,3-dimethyl-l,2-diphenylbuta~-l-ol through the comparative analysis of the respective chemical shifts induced by Eu(fod), in the 'H and '"C NMR spectra, and the corresponding

NMR study of quinolizidine alkaloids: re
NMR study of quinolizidine alkaloids: relative configurations, conformations
✍ Phuong Mai Le; Marie-Thérèse Martin; Nguyen Van Hung; Daniel Guénard; Thierry Sé 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 892 KB

## Abstract Extracts of fruits and leaves of __Connarus paniculatus__ afford six quinolizidine alkaloids which were identified as piptanthine, 18‐epipiptanthine, ormosanine, homoormosanine, podopetaline (monohydrochloride) and homopodopetaline on the basis of high‐field NMR studies. 1D and 2D NMR e

NMR assignments and conformational studi
NMR assignments and conformational studies of two diastereomeric oxidation products of 2′-deoxycytidine
✍ E. Ämmälahti; M. Bardet; J. Cadet; D. Molko 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB 👁 1 views

Structural assignment and conformational features of two diastereomeric oxidation products of 2@deoxycytidine, the 5S\* and 5R\* diastereomers of N1-(2-deoxy-b-D-erythro-pentofuranosyl)-5-hydroxyhydantoin were achieved by combining NMR studies and restrained molecular dynamics. Interproton distances