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Assessment of thermal tissue ablation with MR elastography

✍ Scribed by Tao Wu; Joel P. Felmlee; James F. Greenleaf; Stephen J. Riederer; Richard L. Ehman

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
288 KB
Volume
45
Category
Article
ISSN
0740-3194

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✦ Synopsis

An important part of thermal ablation therapy is the assessment of the spatial extent of tissue coagulation. In this work, the mechanical properties of thermally-ablated tissue were quantitatively evaluated using magnetic resonance elastography (MRE). This study shows that the mechanical properties of focused ultrasound ablated tissue are significantly different from normal tissue, and the difference can be imaged and measured using MRE. Repeated experiments revealed a reproducible pattern of tissue mechanical property change during thermal ablation in ex vivo bovine muscle. This pattern may reflect changes in intrinsic tissue structure and could be used to evaluate tissue coagulation during thermal ablation therapy. Magn Reson Med 45:80 -87, 2001.

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